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After taking Nexium (PPI that blocks all acid) for over 3 years, due to problems with the antibiotics for NTM, I read that PPI's cause bacteria to go into the lungs. Don't need more of that! So now I am going cold turkey, with no Nexium for the past 3 weeks. It is not easy. I have always taken probiotics, but the indigestion is still severe without the Nexium. I take generic antacids that help a little, but nothing like the PPI. Anyone have any experience with this or recommendation? I will ask my pulmo doc and infectious disease doc for advice. PPI's are for short term use and could cause other harmful side effects, also, but they really help with GERD. I no longer take antibiotics at all because of side effects and lack of improvement in my NTM infection. Any ideas would be appreciated.