Completed Studies: Results and Updates

The COPD Foundation partners with external organizations and institutions on Bronchiectasis and NTM research. Below is a list of related research projects in which the COPD Foundation has been involved.

Study Name: Comparative effectiveness and safety of inhaled corticosteroids and antimicrobial compounds for non-CF bronchiectasis

Study Purpose: To evaluate and compare the clinical effectiveness and safety of long-term inhaled corticosteroids and macrolide antimicrobial therapies among a cohort of non-CF bronchiectasis patients.

Study Sponsor: Patient-Centered Outcomes Research Institute (PCORI)

Participating Organizations/Institutions: Oregon Health and Science University and COPD Foundation

Lay Summaries:

• Physician Update on Respiratory Disease Treatment: Inhaled Corticosteroids vs. Oral Antibiotics
• Comparing Treatment with Long-Term Steroids or Long-Term Antibiotics to Prevent Lung Infections in Patients with Bronchiectasis

Scientific Publication(s):

• Henkle E, Curtis JR, Chen L, et al. Comparative risks of chronic inhaled corticosteroids and macrolides for bronchiectasis. Eur Resp J. 2018; 54(1): 1801896. DOI: https://doi.org/10.1183/13993003.01896-2018
• Henkle E, Chan B, Curtis JR, et al. Characteristics and Health-care Utilization History of Patients With Bronchiectasis in US Medicare Enrollees With Prescription Drug Plans, 2006 to 2014. Chest. 2018; 154(6): 1272-1273. DOI: https://doi.org/10.1016/j.chest.2018.07.014

Study Name: Non-cystic fibrosis (CF) bronchiectasis patient network and research roadmap

Study Purpose: To increase patient-centered research capabilities by forming a non-CF bronchiectasis patient network and develop a roadmap for future research.

Study Sponsor: Patient-Centered Outcomes Research Institute (PCORI)

Participating Organizations/Institutions: Oregon Health and Science University and COPD Foundation

Lay Summaries:

• Patient-centered Bronchiectasis Research Roadmap
• Non-Cystic Fibrosis (CF) Bronchiectasis Patient Network and Research Roadmap

Scientific Publication(s):

• Henkle E, Aksamit TR, Daley CL, et al. US Patient-Centered Research Priorities and Roadmap for Bronchiectasis. Chest. 2018; 154 (5), 1016-1023. DOI: HTTPS://DOI.ORG/10.1016/J.CHEST.2018.06.032